Science data needs to be more spatially-enabled, says Nature

Here’s an Editorial from tomorrow’s Nature — link here — on the need for scientists to routinely record spatial data with samples, viral sequences, field observations, and other entities. It proposes a major change in the policies of journals and databases to mandate recording of such data as a prerequisite for having a scientific paper accepted. Feel free to use this blog’s comment facility to express your opinion on this, or email me at declan.m.butler@gmail.com.

During the research for this Editorial, Nature picked up considerable frustration from spatial scientists in many fields about the fact lack of spatial data in otherwise valuable datasets made them all but useless for more quantitative spatial analysis. For the sake of brevity and readability in this short article, we reduced the concept of spatial data to latitude and longitude, but clearly any working system would require more detailed spatial standards, depending on fields.
Continue reading ‘Science data needs to be more spatially-enabled, says Nature’

Agent Orange studies stalled

I’ve the lead news article tonight in Nature with an exclusive — Further delays to full Agent Orange study — on a complex story behind efforts to get done a large-scale epidemiological study of the health effects, and other combat factors — on Vietnam veterans, almost 30 years after it was first mandated. Nature has an accompanying Editorial — A ghost of battles past.

NOTE: All Nature news stories are free online for at least a week to registered users — and registration is FREE.

A few excerpts from the long news article, and the Editorial, below:

A study to investigate the health effects of Agent Orange on Vietnam War veterans is being obstructed by the US Department of Veterans Affairs (VA), claim scientists and veterans’ organizations.

Continue reading ‘Agent Orange studies stalled’

Fighting climate change by architectural design


Ultra-low energy homes are not necessarily architectural boutique projects: above are low-income “passive” terrace houses in Lindas, Sweden

I’ve a 4-page feature in Nature tonight on the huge potential of green architecture for mitigating climate change (pdf file here).

It’s been one of the most challenging articles I’ve had to write, as I had to leave out so much, but at the same time one of the most satisfying. This is a hugely important topic. Buildings account for up to half of all energy consumption, and are the biggest single contributor to greenhouse gas emissions. Much attention is given to exotic future remedies, such as carbon sequestration and clean coal. But a way to slash emissions using existing technologies is sitting under our noses: simply rethinking how we design the buildings we live and work in, to use much less energy.

The arguments for building with energy needs met largely by marrying with the local environment and passive strategies are so compelling that the research for this article is persuading me to switch my own plans to buy a place in French Touraine, where I live, to instead build a zero-energy home — no small challenge though, given that French builders are far behind their German, Swiss, and Austrian neighbours here.

I’ve posted just a few of the links I collected during the research to here on Connotea, and hope to add more.

It’s impossible to excerpt from an article of this length in any sensible way, but just to give you a flavour, here below are a few:

Continue reading ‘Fighting climate change by architectural design’

Iran’s nuclear programme

On 12 February, I wrote a detailed and neutral analysis of Iran’s nuclear programme and its potential capacity to produce weapons. The article was in anticipation of the report by IAEA on Iran sent to its board today, that was intended to wrap up the IAEA’s investigation of Iran’s past and present nuclear activities. The report is classified until 3 March, but has been leaked, and I append a full copy below fyi – as with WHO, other intergovernmental, and government, reports you need to understand diplomatic speak fluently to understand the nuances.

My earlier article also included 2 short boxes — one on the main outstanding issues that IAEA still had to obtain satisfactory answers to, and another on potential weapons break-out scenarios.

Today’s report by the IAEA reveals a disappointing lack of progress, far short of the agency’s expectations. But there is nonetheless reason to believe that reason may yet prevail in this charged dossier, where excessive belligerence on all sides has stalled an acceptable resolution.

I’ve appended below some excerpts from my earlier articles, which may help interpret the new IAEA report. For more detailed analyses of the technical issues in the Iran case, I’d recommend the site of the Institute for Science and International Security, and a January article in the Bulletin of the Atomic Scientist by Richard Garwin, a former nuclear weapons designer who is now a major force for disarmament. Another good source of information is the Nuclear Threat Initiative. The IAEA page on Iran is here.

Abridged excerpts from my earlier articles, and the full text of the new IAEA report appended below:
Continue reading ‘Iran’s nuclear programme’

Nuclear proliferation — a wake-up call

After the success of the international mobilization in the Libya hostage crisis, I’ve been informing myself, through discussions with many people, as to what are the most pressing issues, where change could be made, and influence and impact exercised, by similarly raising awareness among both the public and those well-placed to create change. With US elections this year, and the review conference of the nuclear non-proliferation treaty (NPT) coming up in 2010 — which in intergovernmental terms is tomorrow — I’ve no doubt as to what is one of the most pressing issues of our time. It is nuclear proliferation, and it is a way more complex issue than just Iran or rogue states. And we have a window of opportunity to make progress on it now. The first step is becoming informed; it’s not an easy topic to grasp in all its complexity, but it is well worth it.

I’ve been happy that in this month of January 2008 alone, Nature has dedicated 2 editorials to the topic, and 3 news analyses — it is going to be a topic that you will hear much more about on this blog throughout this year.

Here are the links to the Nature articles from this month:
1. Resurgent nuclear threats
2. Nuclear war: the threat that never went away
3. Nuclear war: the safety paradox
4. Fuel’s paradise
5. Nuclear fuel: keeping it civil

Excerpt of one editorial: Continue reading ‘Nuclear proliferation — a wake-up call’

Q&A with Larry Brilliant, executive director of Google.org

I had a chat last week with Larry Brilliant, executive director of Google.org, Google’s philanthropic arm, which plans to tackle emerging diseases, climate change and poverty. I’ve tried to distill this into what’s known in journalism jargon as a Q&A format in this article in Nature tonight.

Brilliant has had a fascinating career; for a quick summary see the Wikipedia entry on him, including being involved in the eradication of smallpox. His TED talk can be found here, and while we are at TED, here are two must-watch TED talks on bringing health and poverty data to life by Hans Rosling from the Karolinska Institute — who is at Google.org at the moment. We gave Hans’s work a nod in a recent Nature editorial

Brilliant faces a major challenge in mapping out a coherent and effective strategy, but with Google’s resources and networks behind it, Google.org could be a real force for change; I for one will be watching the development of this young organization, which is still naturally finding its feet, with great interest.

Here are some excerpts from the Q&A with Larry Brilliant:

The grants Google.org announced last week were small compared with those made by the Gates Foundation’s Global Health Program.

It’s too early for substantial funding but Google has set aside a generous amount for philanthropy — 1% of equity and 1% of profit. We’ve invested a total of US$75 million so far, but I consider these mostly exploratory grants. It is the beginning of a long process and we will be ramping up giving in the future.


How will the organization work to anticipate new pandemics?

With our ‘Predict and Prevent’ initiative we hope to develop an entire new science of epidemiology and surveillance, both for existing diseases and to spot emerging ones early on. One way is to strengthen national health services — look at the polio surveillance system in India, for example, which is the finest for any disease. We are now funding the Global Health and Security Initiative’s work on the Mekong Basin Disease Surveillance network, to boost diagnostic capacities, train people and help create a regional surveillance network for this hotspot, which covers Cambodia, China, Laos, Myanmar, Thailand and Vietnam. It is also using tabletop planning exercises with modern war-gaming techniques to better prepare a pandemic response. The Mekong project is about creating best practices that can then be transposed elsewhere. It’s all about sharing data, visualizing data and creating the IT tools that people would like these countries to have to mount fast and effective responses.

I see Google is also involved in biology.

We want to detect emerging pandemic agents. Humans are increasingly coming into closer contact with animals in many places, creating hotspots where new diseases emerge by jumping the species barrier. So we plan to support work that takes paired blood samples from animals eaten for bushmeat in Africa, and from their hunters. This will create genomic maps of the viruses present, and reveal how these agents change over time. It’s part of an entirely new chain of information gathering, which at some point will need to be centralized by the World Health Organization, the World Organisation for Animal Health or a non-governmental organization.

How are your relations with the Bill & Melinda Gates Foundation?

I love the Gates Foundation, they are wonderful people, and we will work with them. They have been so kind to me and Google.org. They invited us round to help us understand philanthropy and how it can best be used. When I heard Bill and Melinda speaking recently on their commitment to malaria, I had tears in my eyes.

And here’s one important question that got cut because of space:

Have you a message for Nature’s scientist and other readers?
Look at Google.org’s goals, and if convergent, they should articulate a way that they think they can help, and write to the relevant groups leader. We are looking for partners everywhere.

A very mysterious foundation


That’s the title of an article I’ve in Nature tonight on the World Innovation Foundation, a Bern-based charity, which I found operates in fact largely out of a one-man building consultancy in Huddersfield, a town in Northern England.

Some excerpts

Some 3,000 scientists, including more than 100 Nobel laureates, have apparently accepted membership of a body called the World Innovation Foundation (WIF), which claims to be a powerful world-changing network to provide “the technological tools and miracle technologies that we shall all need to solve the world’s impending global problems”.

No fewer than four Nobel laureates hold executive positions in the WIF’s governance, according to its website: Jerome Karle, William Knowles, Robert Huber, and Yuan Lee. Huber, described as vice-president, claims that he has no recollection of joining the organization. “I am not aware what this organization is,” he says.

Yuan Lee, a 1986 Nobel laureate in chemistry, says he has had “very limited” involvement with the foundation that amounted to accepting a 2002 invitation to join, signing a WIF letter opposing the Iraq war, and accepting in 2004 the position of the WIF ‘national representative’ in Taiwan. Since accepting this position he has had no dealings with the WIF, he says.

Nature polled several WIF fellows who advertise their fellowships on their websites. What emerges is a pattern whereby scientists join on the strength of the list of existing members, but know little about the foundation or its activities.

Continue reading ‘A very mysterious foundation’

“Don’t make the mistake of looking for the future in your rear-view mirror.”

I love this quote; it’s the sort of inspirational one that you’re tempted to stick above your computer screen. It’s from Vinod Khosla, a veteran entrepreneur who co-founded Sun Microsystems, was a partner in Kleiner Perkins Caufield & Byers in Menlo Park, California — the company that nurtured the likes of Amazon, Google and Genentech — and who now heads Khosla Ventures, also in Menlo Park, one of the most prominent clean-energy venture-capital firms

It’s from a two-page article I published tonight in Nature, which details what is probably one of the most significant trends in energy research for over 40 years: the current huge interest of venture capitalists in green energy. As the article makes clear, this is more than a fad, but a potentially world changing development.

Excerpts:

Silicon Valley is greening. Investors are flocking to low-carbon (clean) energy technologies, fuelling a boom in the sector, with investments set to overtake those in Internet start-ups. But does this venture-capital explosion herald another dotcom bubble?

Continue reading ‘“Don’t make the mistake of looking for the future in your rear-view mirror.”’

Earth monitoring special in Nature

Nature has a special issue on Earth monitoring out tonight.

Excerpt

Nearly fifty years ago —things were up and running by March 1958 — Charles Keeling and colleagues began a series of measurements of atmospheric CO2 on Mauna Loa in Hawaii. The results, made graphic in the jagged ‘Keeling curve’ running across this week’s cover, made the world take notice — eventually. The Mauna Loa measurements constitute the longest continuous record of atmospheric CO2 in the world. The steady rise in CO2 that they record now forms the accepted backdrop to today’s climate science and economic and political decision making. As well as being an important resource in itself, the Mauna Loa record highlights the vital importance of Earth monitoring programmes. The fiftieth anniversary of the start of this work is marked in this issue by News Features and other pieces on the Earth monitoring being done today, historical pieces on the Mauna Loa data and more.

I’ve a long futuristic article in the special looking at how close we might be to a totally monitored Earth by 2025: Earth Monitoring: The planetary panopticon

Nature itself has an great editorial — Patching together a world view — which provides a great big picture view, that I’d have struggled to write, so kudos to my colleagues who did such a good job of capturing succintly such a vast topic.

Alex Witze then contrasts my upbeat forecast with the lack of leadership of, and the disarray in, the US’s current Earth monitoring programmes — Earth Observation: Not enough eyes on the prize.

And the journalistic content doesn’t stop there: there are also features on:
Earth Monitoring: Observing the ocean from within

Earth Monitoring: The crucial measurement

And to finish it all off there are two Commentaries by scientists
Earth monitoring: Cinderella science
Earth monitoring: Vigilance is not enough

And an online version of all is here, including a timeline of Earth monitoring.

The Freeing of the Tripoli Six: The inside story of how scientists saved medical workers from the firing squad.

I haven’t been blogging for a while; been taking some time out for other projects, and the blog had become almost entirely devoted to original posts on the Libya death penalty case, a hard act to follow. An article in the November issue of Discover magazine, now free online, provides an opportunity to close that chapter, and start blogging on more mundane matters. The long article, by John Bohannon, a journalist colleague who writes for several science publications including Science, tells the story of scientists’ actions in the Libya case. It covers many of the events blogged here as they happened — see summary here — but as a gripping detective story — it makes a good read.

Excerpts:

Late in September 2006, Nobel Prize–winning molecular biologist Richard Roberts was thumbing through the journal Nature when he read an article by one of their senior reporters, Declan Butler, about a group of foreign medics on death row in Libya. Butler’s article, along with an anonymous editorial entitled “Libya’s Travesty,” described how the medics’ appeals were nearly exhausted. “I had been aware of the situation through the media,” says Roberts, the chief scientific officer at New England Biolabs in Ipswich, Massachusetts. “But the case seemed so open-and-shut, I’d assumed that diplomacy would sort the situation out.” But as the editorial warned, “Diplomacy has lamentably failed to deliver,” and “scientific leaders need to use all their influence” to persuade their governments to take action.

“It was a call to arms,” says Roberts. So he picked up the phone and contacted Butler, who painted a grim picture of the situation. Ever since the death sentence was handed down in 2004, the absurd case had been bouncing between Libya’s courts as the medics languished in jail; there had been at least one suicide attempt among them. Butler was glad Roberts wanted to help. After watching the Libyan affair from a journalist’s vantage point, says Butler, “I found myself in a position to be useful. What was needed was for someone to work behind the scenes, connecting influential scientists with each other and with diplomats involved with the case.”

Continue reading ‘The Freeing of the Tripoli Six: The inside story of how scientists saved medical workers from the firing squad.’

Nature calls for exoneration of medics in Libyan case

Almost one year ago, Nature ran a blistering Editorial — “Libya’s Travesty” — on the tragic case of the HIV medics in Libya. Much water, and many articles in Nature have passed under the bridge since then, and tonight we publish perhaps our last Editorial on the case — “Free at last” — calling for Libya to go beyond the welcome political solution found to have them released, and at last face up to the facts. Exonerate the medics, is the message.

The Editorial in September 2006 was written at a time when the medics faced a serious threat of execution, and began:

Imagine that five American nurses and a British doctor have been detained and tortured in a Libyan prison since 1999, and that a Libyan prosecutor called at the end of August for their execution by firing squad on trumped-up charges of deliberately contaminating more than 400 children with HIV in 1998. Meanwhile, the international community and its leaders sit by, spectators of a farce of a trial.

Implausible? That scenario, with the medics enduring prison conditions reminiscent of the film Midnight Express, is currently playing out in a Tripoli court, except that the nationalities of the medics are different. The nurses are from Bulgaria and the doctor is Palestinian

Excerpts from tonight’s editorial are below, written in a different context now that their liberation has been achieved. But fundamental human rights issues have not yet been resolved, however, and so we demand that Libya now also finally face up to the scientific realities of this case.

In France this week, Libyan leader Muammar al-Gaddafi’s son Seif al-Islam Gaddafi — who played a significant role in resolving the case — declared that the six were “scapegoats” in a “made-up conspiracy” by Libyans, and that the outbreak was as we have long said, an accident.

His statements are courageous, and are to be welcomed; can Libya’s government now show the same balls, and give the six the least they deserve, after all they have suffered as innocent victims of a bigger geopolitical game - having their names cleared? It doesn’t seem like a lot to ask, under the circumstances. Is Libya big enough?

An important para in the Editorial below is this:

“The scientists quickly learned that effectiveness in such matters demanded tight liaison with defence lawyers and human-rights groups. One-off appeals and letters of protest can have some impact in raising public awareness, but effective advocacy requires sustained action, clear objectives and a strategy to achieve them.”

It gives a hint of the behind-the-scenes networking needed to work on this complex case, and I’d like to mention in particular among human rights groups, Physicians for Human Rights, who have really worked hard on the case.

Excerpts

Editorial

The six medical workers held for eight years in a Libyan prison on false charges of deliberately infecting hundreds of children with HIV were finally freed last week. But Libya’s cynical insistence on their guilt is casting a pall over this long-awaited event.

Late in the negotiations that saw the medics’ sentences commuted from the death penalty to life imprisonment followed by their extradition to Bulgaria, Libya refused a request for the final settlement to state that it did not represent an admission of guilt. When Bulgaria freed the six, Baghdadi Mahmudi, Libya’s prime minister, denounced the pardon as a “betrayal”, arguing that the medics should have served life sentences. It is time for Libya to end this charade.

An important supporting role was played by scientists who took up the medics’ cause, including Nobel laureate Rich Roberts of New England Biolabs; Vittorio Colizzi, an AIDS researcher at Tor Vergata University in Rome; and Luc Montagnier, whose group in Paris discovered HIV. They all persistently dissected the emptiness of the prosecution case, showed multiple avenues of evidence pointing to a hospital infection as the true cause of the outbreak and campaigned tirelessly.

The scientists quickly learned that effectiveness in such matters demanded tight liaison with defence lawyers and human-rights groups. One-off appeals and letters of protest can have some impact in raising public awareness, but effective advocacy requires sustained action, clear objectives and a strategy to achieve them.

Libya has, unfortunately, won plaudits in parts of the Arab world for the way it has played its hand, winning normalization of its political and economic ties with the European Union (EU) and much else besides for releasing the six. The EU and the United States should make further normalization contingent on the Libyan government owning up to the real facts of the case, and exonerating the six.

Liberty, Justice, HIV and Libya

Richard Charkin, the chief executive officer of Macmillan Publishers, the parent company of Nature kindly invited me to write a guest post today for his blog, Charkin Blog. The guest post is here, but I thought I’d also post a copy here.

Liberty, Justice, HIV and Libya

The liberation of six foreign health workers, held hostage in Libya, is a welcome denouement of this tragic affair. Today, the 5 Bulgarian nurses and a Palestinian medic woke up in Bulgaria, free at last from the threat that one morning, they might have woken up only to be instead led out, blindfolded, tied to a stake, and executed by firing squad. But the moral price of securing release of the hostages has been high.

The EU humanitarian aid package for over 400 infected Libyan children accidentally infected at a Benghazi hospital is desirable and commendable. But Libya’s tying it to the six’s release, in effect a ransom, sets a dangerous precedent for future unjustly condemned prisoners.

How much more ransom was really paid in the murky deal between the European Union and Libya will probably never be known. The $400 million in ‘blood money’ paid to the families of the infected children from an opaque international fund – which paved the way for the end of the crisis — may in fact have largely been paid by Libya, as part of a complex face saving deal. But Libya extorted concessions on debt relief, and many other fronts. The EU has also promised returns by normalizing its political and economic ties with Libya.

Moreover, Libya set the tempo for the prearranged choreographed diplomatic script. The sequence of the sorry spectacle went like this.

The Supreme Court upholds the death sentence to play to domestic opinion by being seen to stand up to the West, and to avoid calling into question the farce of a trial conducted by its judicial system.

The families then get bought off to gracefully pardon the medics. The Supreme Council then stalls for days, keeping the West waiting at its feet, before finally commuting the death sentences to life imprisonment, and opening the way for extradition of the six to Bulgaria.

Instead of extraditing the medics immediately, Libya continued its bad faith, knowing that with the West so close to resolution of the crisis, it could still try to raise its price. Right until the final hour of their release, Libya haggled as if the medics were carpets in a Tripoli souk, and used delaying tactics, to win further concessions.

In short, the West has been forced to appease Libya, and ultimately reward it for taking six health workers hostage for eight years. This all is difficult to swallow. The six were not given a fair trial, prosecution evidence was fabricated, and scientific evidence that would have exonerated the medics ignored. Their trials were a kafkaesque mockery that trampled on justice.

But that outcome was perhaps inevitable. From the outset, the six were pawns, caught up in global geopolitics. Once sucked into that quagmire, respect for fundamental human rights such as the right to a fair trial, became just one element in a wider basket, that included Libya’s renunciation of weapons of mass destruction, it’s utility as an ally in the war against terror, not to mention that Libya’s coming in from the cold opened up to for Western economic interests the goldmine of the world’s largest unexplored oil reserves.

Once the case had become politicized, it was inevitable too that the solution would have to be political. The campaigns by Nature, human rights groups, scientific organizations and lawyers, acknowledged this reality from the outset, and understood well that the only real pressure point available was to raise international public opinion and awareness to force Western governments to do more to resolve the case.

As well as defending the fundamental principles of a fair trial, and the right for relevant evidence to be heard, the focus on calling for the scientific evidence to be heard was considered by the defence as its best card in the run up to the end of the trial last autumn.

Had Libya accepted to have had the scientific evidence heard in court, the prosecution case would have collapsed like a pack of cards. But if as was most likely, it refused to do so, it would also expose with clarity that the trial was anything but fair, and provide a fulcrum, a focus, to leverage public opinion, and consequently political opinion.

The massive international outrage after the 19 December death penalty verdict was in large part prompted by the fact that science had demonstrated the emptiness of the prosecution case, leaving the world in no doubt that this was an appalling miscarriage of justice. The scale of the outrage led to more intense diplomatic activity, in particular by the EU.

The human rights case was also not entirely lost. After the verdict, the EU broke temporarily with its policy of ’silent diplomacy’ — refraining from public criticism of Libya’s handling of the case and relying on behind-the-scenes discussions – and condemned in no uncertain terms the human rights violations, and abuse of scientific evidence in the case. This, combined with the fact that Bulgaria became a member of the European Union at the start of the year, led to pressure for a speedy resolution of the case.

The United States meanwhile has been absent from the case, and mute on the human rights abuses in the case. Its absence though was perhaps not a bad thing after all, given the current administration’s own abyssmal record on human rights, which deprive it of moral authority.

Unbelievable perhaps though, that the administration couldn’t find anything better to do on 11 July, the day the Libyan Supreme Court upheld the death verdict, than to announce it would appoint an ambassador to Tripoli for the first time in more than 25 years.

Realpolitik all along meant that the six could probably never have hoped that the international community would force Libya to give the six a fair trial. That the medics are free at last is already a major victory, and hat’s off to the EU and British diplomats who worked patiently to put together a solution to the case – they are right to be livid with France and the Sarkozy family’s shameless attempt to steal the limelight and take all the credit for the release.

The 1998 outbreak was a triple tragedy — for the six unjustly imprisoned, and for the infected children and families. Exoneration of the medics must be the next step. And as Vittorio Colizzi, an AIDS researcher at Tor Vergata University in Rome, Italy, who campaigned for scientific evidence exonerating the medical workers to be considered by the Libyan courts, says: “We must not forget the children.” The third victim, which has not often been mentioned, is the struggle to have nation states abide by the fundamental international principles of justice and human rights enshrined in treaties to which they are, on paper, parties to.

Declan Butler

Freedom!

By now you will all have heard the good news that the six foreign health workers have finally been freed. I’ve written an update in Nature tonight — Libyan ordeal ends: medics freed.

I’d like to thank the many hands, from the EU and British diplomats who worked patiently behind-the-scenes, to the many bloggers, scientists, journalists, lawyers, and human rights groups, who have all contributed to resolution of this politically-complex case.

It has been a long and tumultuous campaign, and over the past months, I’ve had the pleasure and opportunity of working closely with many incredibly committed people all pulling in the same direction to achieve one goal — today’s liberation — with many of their efforts often far from the public glare of the cameras.

Today is a great day, so let’s celebrate it. The full legal and diplomatic history of this case will take time to dissect, as will its implications. On the longer-term implications, Physicians for Human Rights, an organization that has been highly-active behind the scenes has issued a very pertinent statement tonight — “Exonerate Pardoned Bulgarian Nurses and Palestinian Medic“.

And as Vittorio Colizzi, an AIDS researcher at Tor Vergata University in Rome, Italy, who campaigned for scientific evidence exonerating the medical workers to be considered by the Libyan courts, says: “We must not forget the children.” The 1998 outbreak was a double tragedy — for the six unjustly imprisoned, and for the infected children and families.

And as a historical note, here’s a list of everything Nature published on this case recently

Libyan ordeal ends: medics freed

Declan Butler
News@nature.com (24 July 2007) doi:10.1038/448398a

High noon in Libya

Declan Butler
News@nature.com (17 July 2007) doi:10.1038/448230a

Libyan court upholds death sentences

Declan Butler
News@nature.com (11 July 2007) doi:10.1038/news070709-6

Supreme Court hearing starts for medics facing death penalty
Declan Butler
News@nature.com (20 June 2006) doi:10.1038/news070618-12

Diplomatic talks spur hope in Libya HIV case

Nature 447, 624—625 (7 June 2007) doi:10.1038/447624b

Libya and human values
Nature 445, 2 (4 January 2007) doi:10.1038/445002a

Europe condemns Libyan trial verdict
Declan Butler
Nature 445, 7 (4 January 2007) doi:10.1038/445007a

Medics sentenced to death in Libya
Declan Butler
News@nature.com (18 December 2006) doi:10.1038/news061218-3

Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak
Tulio de Oliveira et al.
Nature AOP (6 December 2006) doi:10.1038/444836a

Molecular HIV evidence backs medics
Declan Butler
Nature 444, 658-659 (7 December 2006) doi:10.1038/444658b

Libya death penalty trial ends; verdict 19 December
Declan Butler
News@nature (6 November 2006) doi:10.1038/news061106-3

An open letter to Colonel Muammar al-Gaddafi
Richard J. Roberts and 113 fellow Nobel Laureates
Nature AOP (2 November 2006) doi:10.1038/444146a

A shocking lack of evidence
Declan Butler
Nature 443, 888-889 (26 October 2006) doi:10.1038/443888a

Protests mount against Libyan trial
Declan Butler
Nature 443, 612-613 (12 October 2006) doi:10.1038/news060925-2

Forgotten plights
Nature 443, 605-606 (12 October 2006) doi:10.1038/443605b

Dirty needles, dirty dealings
Charlotte Schubert
Nature 443, (2 October 2006) doi:10.1038/news061002-3

Bloggers rally for liberation of the ‘Tripoli Six’
Declan Butler
news@nature (25 September 2006) doi:10.1038/443612a

Libya’s travesty
Nature 443, 245 (21 September 2006) doi:10.1038/443245b

Lawyers call for science to clear AIDS nurses in Libya
Nature 443, 254 (21 September 2006) doi:10.1038/443254b

Excerpts from my brief article tonight:

A French government aircraft carrying six medical workers convicted of deliberately infecting children with HIV touched down in Sofia, Bulgaria, on 24 July, ending their 8-year ordeal in a Libyan prison.

Their release is the final scene in meticulously crafted negotiations between the European Union (EU) and Libya, which sought a way for Libya to climb down on the case without being seen to concede to Western pressure. Diplomatic efforts intensified as a result of international public and political outcry after the six medical workers were sentenced to death in a retrial on 19 December 2006.

“The efforts to mobilize Western governments to act by increasing international public opinion have paid off,” says Emmanuel Altit, a lawyer from the medical workers’ international defence team. The concerted efforts of the scientific community around the case played a “fundamental role” in changing the trajectory of the case and helping to secure today’s outcome, he adds.

Libya has long used the six medical workers as bargaining chips and political pawns in its international relations. Right until the final hour of their release, Libya haggled to win further concessions to improve its political and trade ties with the EU.

Benita Ferrero-Waldner, the European commissioner for external relations, was also on the aircraft with the freed health workers. She, the EU and Britain, were the main players working patiently behind the scenes to secure the release. On the Libyan side, the key force in freeing the workers was Seif al-Islam Gaddafi, son of the Libyan leader Muammar al-Gaddafi, through his charity the Gaddafi Development Foundation. He is thought to be personally convinced that the outbreak was accidental.

More controversial is the role played by another passenger on the plane, French first lady Cécilia Sarkozy. France has not had a prominent role in the negotiations, and her last-minute intervention is widely considered to be a thinly veiled bid by her husband to steal the limelight that may, in fact, have weakened the EU’s negotiating position in the talks.

High Noon in Libya

Still waiting on a decision from the Supreme Council. Meanwhile, I’ve written a long article in Nature, “High Noon in Libya,” available online tonight, tracing scientists efforts in the case

Update on Libya death penalty case

I’ve a brief update on the Libya case on Nature news online tonight – see ‘ Supreme Court hearing starts for medics facing death penalty ‘ . It’s an update to one earlier this month in Nature — Diplomatic talks spur hope in Libya HIV case.

We are now in the crucial final phase of the Tripoli six case. This morning, Libya’s Supreme Court heard the appeal of the six. There will be no further hearings, and it will rule on 11 July. Meanwhile, the families of the Libyan children are discussing a possible settlement with the European Union, and an announcement on that is expected Friday.

As in the past in this case, details and plans keep shifting — eg until very recently, a verdict had been expected today – but the overall thrust now looks cautiously optimistic for a rapid resolution of the case.

The campaigns by scientists and others to draw attention to the science of this case during the course of the trial last autumn have borne fruit, contributing to the depth of international protests after the 19 December death penalty verdict. This — combined with the fact that Bulgaria became a member of the European Union at the start of the year — – see ‘ Europe condemns Libyan trial verdict‘ – has resulted in increased diplomatic activity, in particular by the EU, to find a solution. Libya too increasingly seems sincerely to want to turn the page on this tragic affair.

Talks have intensified over the past month
, with visits to Libya by Tony Blair, Benita Ferrero-Waldner, the EU Commissioner for External Relations, and Frank-Walter Steinmeier, the German Foreign Minister.

The contours of the solution remain hinged on international humanitarian aid to provide high-quality life-long treatment of the infected children, and support for their families. That’s important, and addresses one of the concerns of the families: that once the spotlight turns away from the case, following any release of the healthcare workers, the children’s care might be forgotten about. With lifelong care, including existing modern anti-retrovirals, as well as anticipated therapeutic advances, the children might expect to lead reasonably normal lives.

The EU’s Ferrero-Waldner, who has condemned the conduct of the medics’s trial, has shown sensitivity to the children’s plight. “We have come here to acknowledge the suffering of the children,” she said 10 June during her Libya visit, “and have understanding and sympathy for the families, who must have been shocked by the horrible events of the AIDS case.”

In terms of negotiating an outcome, she said “I think we have advanced a lot.” Clearly if the families and the EU do reach agreement on a humanitarian package, this will greatly improve the climate for the 11 July ruling – Islamic law can interpret this as blood money, which could allow the charges to be dropped. But irrespective of what the verdict is on 11 July, the death sentences could still be annuled, or commuted, by the Supreme Council for Judicial Authority, a political body spanning Libya’s executive and judiciary authorities.

Amidst the flurry of diplomatic negotiations a key player is Seif al-Islam Gaddafi, a son of the Libyan leader.
He heads the Kadhafi Foundation for Development, a non-governmental charity, and helped mediate the compensation deals for both the bombings of a US airliner over Lockerbie in Scotland in 1988, and of a French airliner over Niger the following year. Those who have met the young Gaddafi have been impressed by what they describe as his thorough grasp of the circumstances of the HIV outbreak, and his sincere commitment to finding a solution.

Many scientists, human rights bodies, lawyers, and others have articulated clearly and publicly throughout this case the principles of the need for justice, a fair and impartial trial, and the proper hearing of scientific evidence.
I think that message has been received, and helped move matters along at an important point in the case. Although exoneration of the medics must be the ultimate goal, the immediate emphasis of European Union diplomats seems more on securing that the six might soon touch down on a tarmac in Sofia. That would already be a large step forward for the six still facing the death penalty in Libya.
Fingers crossed…

Families of Bulgarian nurses meet France’s presidential candidates

The families of the Bulgarian nurses met today in Paris separately with Ségolène Royal and Nicolas Sarkozy. Both candidates pledged to make resolution of the case a priority if elected, and to have it on the agenda at the next EU summit on 22 June. This high-level political support is a very important, and welcome, development in the case.

It’s a pity therefore that there is a slightly bitter aftertaste of political recuperation. TF1, one of the main national TV channels here, again demonstrated its political impartiality by running images of the meeting with Sarkozy as headline evening news, but failing to even mention that the nurses’ families met with Royal. Both meetings were arranged by a coalition of European NGOs and individuals, of which I’m part of.

Moreover the families also met, not only with Royal, but Jack Lang, Royal’s adviser — who a few weeks ago visited the nurses in their prison in Libya — and Robert Badinter, who as Socialist interior minister under Mitterrand, abolished the death penalty in France, and has long been a solid supporter of the nurse’s case, and also contributed his political sagesse and experience to the cause. Political credit should be given in such human rights issues — even by electoral and parochial TF1 — where it is due.

Virtual Globes and environmental science

The UK National Institute for Environmental eScience (NIEeS) recently organized a scientific workshop at Cambridge University on environmental research applications of Google Earth and other virtual globes; some of the presentations are now available online here.

Bush commends Darfur Google Earth layers; I recount the history of the project

For what it’s worth, Georges Bush tonight commended the Darfur layers in Google Earth built by a group of volunteers (including yours truly), and endorsed by Google and the United States Holocaust Memorial Museum. On news@nature.com tonight, I tell the story of how this project evolved.

To read more of that history, see below:
Continue reading ‘Bush commends Darfur Google Earth layers; I recount the history of the project’

Nature on France’s presidential elections

In the week of the first round of France’s presidential elections, Nature takes a unique 9-page look at what the incoming president will mean for French research. Segolene Royal, Nicolas Sarkozy and Francois Bayrou, the only contenders in the race who might ultimately win the presidency, go into unprecedented detail on their plans for French science and technology in response to Nature’s questions.

Continue reading ‘Nature on France’s presidential elections’

Genocide information in Google Earth

I’m pleased to let you know about Crisis in Darfur, a Google Earth layer that assembles data, photographs, and eyewitness testimony and which will be officially announced today by Google and the US Holocaust Memorial Museum. It will appear in Google Earth under the Global Awareness layer in the left hand panel of Google Earth .
Continue reading ‘Genocide information in Google Earth’

Send Senators Joseph Biden and Patrick Leahy an appeal on the Libya death penalty case

Physicians for Human Rights has launched a web page to send a message to the US administration on the need to resolve speedily the case of the medics facing the death penalty in Libya. You can access the sign on page here. Bloggers, please sign up, and forward this link to other bloggers/media. See PHR’s recent letter to Colonel Gaddafi here.
Thanks
Declan

Bianca Jagger to support medics in Libya


Bianca Jagger will arrive in Bulgaria tomorrow to lend support to the “You are not alone” campaign.

George Michael will also hold a concert in May in Bulgaria to back the cause. The two join a list of celebrities moved by the double tragedy; the children infected with HIV, and these health professionals unfairly imprisoned and sentenced to death.

Let’s hope their support can help mobilize public opinion to galvanize ongoing political and diplomatic efforts to alleviate both tragedies.

US Deputy Secretary of State John Negroponte to visit Libya next week


I’ve already posted on the public ambivalence of the US State Dept on the Libya death penalty trial — see post here.

John Negroponte, the number 2 in the State Dept will visit Libya next week, the highest-ranking US official to visit Libya since the US and Libya resumed full diplomatic relations last May. The talks will focus on Darfur. The US must ensure that the case of the six condemned medics is also high on the agenda.

See Reuters report here

“Justice in Libya? Let Scientific Evidence Prevail”


That’s the title of a recent editorial in the Journal of Infectious Diseases, one of the top journals in this field. You can access the full article here.
Concluding paragraph:

How will this sad and deplorable episode end? Six foreign health care workers have now been jailed in Libya for ∼8 years, reportedly tortured, and now once again (on 19 December 2006) sentenced to death. Appeals are being considered, and ransom negotiations continue. Assuming the presumption of innocence as a basis for a fair trial, it must be stated that, by any objective standard, there is no scientific evidence to convict anyone of deliberately infecting unfortunate Libyan children. Moreover, epidemiologic and molecular evidence demonstrates that the HIV strain that caused the nosocomial outbreak was circulating in the hospital before the arrival of the foreign health care workers, and poor hygiene standards, such as the reuse of needles, were reportedly widespread. We can only hope that world pressure will continue until this miscarriage of justice is reversed. As noted by Ahuja et al., what has happened in Libya has sent “a chilling message to all health care workers who choose to work in difficult circumstances to deliver life-saving care to HIV-1–infected or at-risk people worldwide” [9, p. 924]. At a time when enormous progress is being made in the rollout of antiretroviral drugs to the developing world, we can ill afford such chilling messages. Let us all continue to exert whatever individual and collective pressure we can to bring this injustice to an end.

10 major US medical groups call for release of hostages in Libya

In the run up to the Supreme Court hearing of the appeal of 5 Bulgarian nurses and a Palestinian doctor in the death penalty trial in Libya — expected as soon as end month — there will be growing international activity. On 23 March, 10 major medical associations wrote to Colonel Mu’ammar al-Qadhafi arguing the case for the release of what some describe as political and judicial hostages. A coalition of European organizations will be launched this month also.

Exclusive: Joan of Arc’s relics exposed as forgery made from Egyptian mummy

I’ve a quirky but fascinating exclusive in a news article in tonight’s Nature. Here’s the link.

Excerpt:

The relics of St Joan of Arc are not the remains of the fifteenth-century French heroine after all, according to European experts who have analysed the sacred scraps. Instead, they say the relics are a forgery, made from the remains of an Egyptian mummy.

Philippe Charlier, a forensic scientist obtained permission to study the relics — cloth, a human rib and a cat femur — from the French church last year. He says he was “astonished” by the results. “I’d never have thought that it could be from a mummy.”

The researchers used a range of techniques to investigate the remains, including mass, infrared and atomic-emission spectrometry, electron microscopy, pollen analysis and, unusually, the help of the leading ‘noses’ of the perfume industry: Sylvaine Delacourte from Guerlain, and Jean-Michel Duriez from Jean Patou.

A series of clues led to conclusion that the relics were of the mummy origin, reinforced by carbon-14 analysis dating the remains to between the third and sixth centuries BC. And the spectrometry profiles of the relics matched those from Egyptian mummies from the period, and not those of burnt bones. Charlier points out that mummies were used in Europe during the Middle Ages in pharmaceutical remedies.

Millennium development holes

Nature recently published an Editorial “Millennium development holes” on problems with the underlying data used to assess progress to the goals.

Excerpt

Every year, the UN rolls out reports with slick graphics, seemingly noting with precise scientific precision progress towards the goals. But the reports mask the fact that the quality of most of the underlying data sets is far from adequate. Moreover, the indicators often combine very different types of data, making aggregation and analysis of the deficient data even more complicated.

There are decent data for just a handful of indicators, such as child mortality, but for most of the 163 developing countries, many indicators do not even have two data points for the period 1990–2006. And few developing countries have any data for around 1990, the baseline year. It is impossible to estimate progress for most of the indicators over less than five years, and sparse poverty data can only be reliably compared over decades.

Meanwhile, here are links to a few of my recent articles:
Continue reading ‘Millennium development holes’

Nature launches avian flu site

Nature helped launch interest in addressing the risks of a flu pandemic back in 2005. One of may favourites still is the fictional blog I wrote; The flu pandemic: were we ready?

Since then awareness of the threat has grown and there is extensive blog and media coverage on developments, as well as governmental and other sites providing information.
As an archive of reliable scientific information, Nature has now brought all its avian flu content together on one site, with almost all on free access. Here’s the link.

Libya verdict follow-up in Nature

The lead story in the first issue of Nature in 2007 is an update on the Libya death penalty case — link here. It is accompanied by an Editorial — “Libya and human values.” Both should be on free access.

A few excerpts from the Editorial:
Continue reading ‘Libya verdict follow-up in Nature’

Christmas day and Libya death penalty case

I haven’t posted since the death penalty verdict last Tuesday, because I’m still analysing carefully all the different responses and positions. But it is Christmas Day, so I thought I’d post symbolically, just to point out it was on this very day last year that the six were cleared by the Supreme Court of Libya of the charges against them.

One year later, Valya Chervenyashka; Snezhana Dimitrova; Nasya Nenova; Valentina Siropulo; and Kristiana Valcheva, the five Bulgarian nurses, along with Ashraf Ahmad Jum’a, a Palestinian intern trainee doctor, have again been given the death sentence following the 19 December court ruling in the retrial at the Benghazi criminal court.

That is despite the fact that this was not a fair and impartial trial, and that the court refused to hear the considerable body of international scientific evidence that could exonerate the medics, and show that this is a typical hospital-borne spread.

The Libyan children are being treated in European hospitals — thanks in part to a humanitarian fund established by the international community –and this Christmas, our thoughts are also with them and their families. But denial of the problems all health systems face will not help these children, or those children who risk being infected in future through hospital infections in many countries, such as the almost 100 children infected with HIV in a Kazakhstan hospital this summer — see older BBC story here.

Bulgarian media have launched a “You are Not Alone” ribbon campaign for the six — see logo at top of this post. I endorse it, as defending the most basic of human rights; the right to a fair trial. This case is not only about fundamental human rights principles, but also about the role of scientific evidence, and how we face up to, and not deny, the potential health threats to us and our children, posed by deficiencies in all our health systems.

This case should be an issue of health and science, not a power play between governments as it is turning out to be. Let’s get back to the fundamental principles of health, science, and law in this case. And think of the two groups of innocent victims in this case; the six, falsely accused, and the infected children.

Libya condemns Tripoli Six to death

By now, I am sure you all will have heard the grim news from Libya. I’ve written a short factual account here: Medics sentenced to death in Libya.

I’ll blog more later, after taking stock. The six health professionals have 60 days to appeal to the Supreme Court — their ultimate chance to obtain justice.

Background information resources for Libya HIV case

The verdict in the Libya HIV death penalty trial is expected to be announced tomorrow. Here are a few information resources that may be useful if you are blogging or writing about the trial.

The Council of Europe has a good and succint factual account of the case and the human rights violations.
This blog also has a resource page for the trial providing other background, and links to key media Editorials. This WSJ account by Judy Miller, who visited the prisoners recently, is also well worth a read.
ScienceBlogs has considerable coverage.
Nature has a special focus with free access to articles about the trial.
A selection of recent media and blog articles are bookmarked here.
European efforts to help the affected children are described here.

US State Department’s public face on Libya HIV case

Sean McCormack is the US State Department’s official spokesman. But he doesn’t seem to be very well-briefed on the death penalty trial in Libya of 5 Bulgarian nurses, and a Palestinian doctor, accused of injecting over 400 children with HIV, even though the verdict is expected next Tuesday.

Continue reading ‘US State Department’s public face on Libya HIV case’

Libyan scientist defends prosecution case in death penalty trial

This link is to videos of a press conference held in Geneva last Friday, where the speakers defend the prosecution case in the Libya HIV trial.

One speaker is Mohamed Daw, head of the Department of Microbiology at the Faculty of Medicine, al-Fatah University. Daw was one of five independent Libyan experts, who authored of a 2003 report to the court. Here he defends his report; for an independent assessment of this report, see here. He shares the platform with Ramadan Ali El Faiture, speaking on behalf of the infected children and families.

I will leave you to judge for yourself the depth, rigour, and validity, of the scientific evidence presented.

Google Earth avian flu maps updated

I’ve updated the flu maps to this weekend — link here.. Since August, the spread of avian flu, as reported, has shown a lull, with only a few animal outbreaks, reported, in Indonesia, Vietnam, Cambodia, Egypt, China and South Korea. Over the same period there have been 10 human cases in Indonesia, and 1 in Egypt.
Continue reading ‘Google Earth avian flu maps updated’

Leading international medical bodies plead for charges to be dropped in Libya case after new scientific evidences


Citing the new scientific evidence published in Nature this week, “the World Medical Association and the International Council of Nurses have sent a joint letter to the African Union, Amnesty International, the Libyan Government, the Council of Europe and Physicians for Human Rights drawing their attention to new scientific findings casting doubt on the evidence against the accused health professionals.”

The full text of their statement is given below. The World Medical Association,represents more than eight million physicians worldwide. The International Council of Nurses is a federation of 129 national nurses’ associations representing 13 millions nurses worldwide.

Full text below:

Continue reading ‘Leading international medical bodies plead for charges to be dropped in Libya case after new scientific evidences’

New scientific evidence in Libya death penalty case